ASPxFormLayout provides you with an ability to flexibly customize form layouts by dividing group contents into table cells and position layout elements (items and groups) within cells which can span across several columns or rows. So, the layout of elements in a group can be customized in a manner similar to an HTML TABLE element using colspan and rowspan notions.
You can use a group's ColCount property to define the number of logical columns within the group. All layout elements (items and groups) have the ColSpan and RowSpan properties allowing you to span them across multiple table cells.
In this demo, a group's ColCount property is set to 3, and the memo editor spans across three columns due to its ColSpan property set to 3.